Transnasal Transsphenoidal Surgery: A Minimally Invasive Approach to Brain Tumors
Transnasal Transsphenoidal Surgery (TNTS) is an advanced and minimally invasive surgical technique primarily used to remove tumors located at the base of the brain, such as pituitary adenomas and certain skull base tumors. This approach provides surgeons access to the brain through the nose, avoiding large incisions and reducing risks associated with traditional brain surgeries.
Technological Support in TNTS
Surgeons often use advanced tools like:
- Neuro-Navigation Systems: GPS-like technology to guide the procedure with precision.
- Endoscopes: High-definition cameras for detailed visualization.
- Specialized Microsurgical Instruments: For delicate tumor removal.

How Transnasal Transsphenoidal Surgery Works
- Nasal Access: The surgeon uses the nasal cavity as a natural pathway to reach the sphenoid sinus, which lies close to the base of the brain.
- Sphenoid Entry: The sphenoid bone is carefully opened, allowing direct access to the tumor.
- Tumor Removal: Using advanced surgical tools and sometimes an endoscope for visualization, the tumor is safely removed without disturbing healthy brain tissue.
Advantages of Transnasal Transsphenoidal Surgery
- Minimally Invasive: No external scars as the surgery is performed entirely through the nose.
- Faster Recovery: Patients typically experience shorter hospital stays and quicker recovery times.
- Reduced Risks: Avoids opening the skull, minimizing complications like infections or significant blood loss.
- Precision: Surgeons use advanced neuro-navigation and endoscopic technology for highly accurate tumor removal.
Conditions Treated with TNTS
- Pituitary Adenomas: Benign tumors of the pituitary gland.
- Craniopharyngiomas: Rare tumors near the pituitary gland.
- Rathke's Cleft Cysts: Non-cancerous growths near the pituitary.
- Certain Skull Base Tumors: Tumors located at the base of the brain or near the sphenoid sinus.